HitPredict

Interactor 1: EPHA8 (P29322)
Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)
Gene: EPHA8

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1005 Hs			1 999
+	Hs
		665690 EPHB2_HUMAN (31-1005): 0: 1211: 49.95		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		665505 EPHA8_HUMAN (1-1005): 0: 1245: 100.00		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		1072565 EPHA7_HUMAN (5-1005): 0: 1236: 56.16		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320817 EPHA8_HUMAN (1-1005): 0: 1245: 100.00		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		1128944 EPHAA_HUMAN (2-1005): 0: 1050: 44.29		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		320868 EPHAA_HUMAN (2-1005): 0: 1050: 44.29		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		674576 UFO_HUMAN (264-981): 3.57e-161: 499: 22.34		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		503499 EPHB2_HUMAN (31-1005): 0: 1211: 49.95		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		1018377 MERTK_HUMAN (266-937): 4.55e-151: 475: 22.71		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		987311 TYRO3_HUMAN (264-987): 2.51e-149: 468: 21.12		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		411535 INSR_HUMAN (377-935): 6.29e-143: 463: 25.85		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		972379 TIE2_HUMAN (328-897): 9.41e-141: 452: 26.28		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		411458 INSR_HUMAN (377-935): 6.29e-143: 463: 25.85		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320795 INSR_HUMAN (377-935): 6.29e-143: 463: 25.85		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		412286 FYN_HUMAN (629-900): 6.44e-59: 213: 41.76		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		412053 FYN_HUMAN (629-900): 6.44e-59: 213: 41.76		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		503517 UFO_HUMAN (264-981): 3.57e-161: 499: 22.34		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		564014 UFO_HUMAN (264-981): 3.57e-161: 499: 22.34		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		411965 FYN_HUMAN (629-900): 6.44e-59: 213: 41.76		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42