HitPredict

Interactor 1: EPHB2 (P29323)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: ECHA (P40939)
Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (Monolysocardiolipin acyltransferase) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]
Gene: HADHA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044877 - protein-containing complex binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1055 Hs			1 763
+	Hs
		778157 EPHA7_HUMAN (6-982): 0: 1154: 57.46		ECHA_HUMAN (1-763): 0: 942: 100.00
+	Hs
		778087 EPHA4_HUMAN (6-982): 0: 1152: 58.33		ECHA_HUMAN (1-763): 0: 942: 100.00
+	Hs
		778086 EPHA5_HUMAN (6-984): 0: 1148: 56.69		ECHA_HUMAN (1-763): 0: 942: 100.00
+	Hs
		674351 UFO_HUMAN (266-950): 2.71e-152: 477: 23.12		ECHA_HUMAN (1-763): 0: 942: 100.00
+	Hs
		435569 IGF1R_HUMAN (347-885): 2.31e-146: 474: 27.31		ECHA_HUMAN (1-763): 0: 942: 100.00
+	Hs
		601476 FGFR2_HUMAN (392-932): 6.72e-145: 455: 22.69		ECHA_HUMAN (1-763): 0: 942: 100.00
+	Hs
		671540 EPHA6_HUMAN (16-983): 0: 1111: 52.32		ECHM_HUMAN (1-292): 1.26e-79: 258: 24.83
+	Rn
		431429 INSR_RAT (280-937): 2.81e-145: 471: 24.56		ECHP_RAT (43-763): 0: 740: 28.69