HitPredict

Interactor 1: EPHB2 (P29323)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: EAA1 (P43003)
Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3)
Gene: SLC1A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0043025 - neuronal cell body
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1055 Hs			1 542
+	Hs
		792754 EPHA4_HUMAN (6-982): 0: 1152: 58.33		EAA3_HUMAN (40-534): 1.38e-178: 515: 54.93
+	Hs
		1072504 EPHA7_HUMAN (6-982): 0: 1154: 57.46		AAAT_HUMAN (37-517): 1.92e-150: 443: 43.86
+	Hs
		665400 EPHA3_HUMAN (16-980): 0: 1152: 56.37		AAAT_HUMAN (37-517): 1.92e-150: 443: 43.86
+	Hs
		872653 EPHA4_HUMAN (6-982): 0: 1152: 58.33		AAAT_HUMAN (37-517): 1.92e-150: 443: 43.86
+	Hs
		872446 EPHA5_HUMAN (6-984): 0: 1148: 56.69		AAAT_HUMAN (37-517): 1.92e-150: 443: 43.86
+	Hs
		674356 UFO_HUMAN (266-950): 2.71e-152: 477: 23.12		EAA3_HUMAN (40-534): 1.38e-178: 515: 54.93
+	Hs
		674443 UFO_HUMAN (266-950): 2.71e-152: 477: 23.12		AAAT_HUMAN (37-517): 1.92e-150: 443: 43.86