HitPredict

Interactor 1: EPHB2 (P29323)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: CYFP1 (Q7L576)
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
Gene: CYFIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005829 - cytosol GO:0007411 - axon guidance GO:0043025 - neuronal cell body GO:0043197 - dendritic spine
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1055 Hs			1 1253
+	Hs
		665645 EPHB2_HUMAN (20-1055): 0: 1304: 100.00		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		1072531 EPHA7_HUMAN (6-982): 0: 1154: 57.46		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		1072571 EPHA7_HUMAN (6-982): 0: 1154: 57.46		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		872688 EPHA4_HUMAN (6-982): 0: 1152: 58.33		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		600647 EPHA1_HUMAN (12-976): 0: 961: 41.21		CYFP2_HUMAN (1-1253): 0: 2070: 85.92
+	Hs
		433396 YES_HUMAN (572-881): 5.77e-65: 231: 42.95		CYFP1_HUMAN (1-1253): 0: 2086: 100.00
+	Hs
		433444 YES_HUMAN (572-881): 5.77e-65: 231: 42.95		CYFP2_HUMAN (1-1253): 0: 2070: 85.92