HitPredict

Interactor 1: EPHB2 (P29323)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: JPH3 (Q8WXH2)
Junctophilin-3 (JP-3) (Junctophilin type 3) (Trinucleotide repeat-containing gene 22 protein)
Gene: JPH3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007612 - learning GO:0048168 - regulation of neuronal synaptic plasticity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1055 Hs			1 748
+	Hs
		665434 EPHA3_HUMAN (16-980): 0: 1152: 56.37		JPH1_HUMAN (4-747): 1.2e-164: 492: 47.59
+	Hs
		1336750 EPHA6_HUMAN (16-983): 0: 1111: 52.32		JPH1_HUMAN (4-747): 1.2e-164: 492: 47.59
+	Hs
		665531 EPHA8_HUMAN (20-982): 0: 1066: 50.71		JPH1_HUMAN (4-747): 1.2e-164: 492: 47.59
+	Hs
		665338 EPHA2_HUMAN (18-980): 0: 1041: 47.98		JPH1_HUMAN (4-747): 1.2e-164: 492: 47.59
+	Hs
		600677 EPHA1_HUMAN (12-976): 0: 961: 41.21		JPH1_HUMAN (4-747): 1.2e-164: 492: 47.59
+	Hs
		411501 INSR_HUMAN (277-941): 5.94e-150: 484: 24.02		JPH1_HUMAN (4-747): 1.2e-164: 492: 47.59
+	Hs
		601599 FGFR2_HUMAN (392-932): 6.72e-145: 455: 22.69		JPH1_HUMAN (4-747): 1.2e-164: 492: 47.59