HitPredict

Interactor 1: EPHB2 (P29323)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: NTPCR (Q9BSD7)
Cancer-related nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) (Nucleoside triphosphate phosphohydrolase)
Gene: NTPCR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1055 Hs			1 190
+	Hs
		1072584 EPHA7_HUMAN (6-982): 0: 1154: 57.46		NTPCR_HUMAN (1-190): 2.26e-106: 304: 100.00
+	Hs
		872700 EPHA4_HUMAN (6-982): 0: 1152: 58.33		NTPCR_HUMAN (1-190): 2.26e-106: 304: 100.00
+	Hs
		872480 EPHA5_HUMAN (6-984): 0: 1148: 56.69		NTPCR_HUMAN (1-190): 2.26e-106: 304: 100.00
+	Hs
		665518 EPHA8_HUMAN (20-982): 0: 1066: 50.71		NTPCR_HUMAN (1-190): 2.26e-106: 304: 100.00
+	Hs
		171329 EPHB6_HUMAN (20-985): 0: 927: 46.28		NTPCR_HUMAN (1-190): 2.26e-106: 304: 100.00
+	Hs
		411487 INSR_HUMAN (277-941): 5.94e-150: 484: 24.02		NTPCR_HUMAN (1-190): 2.26e-106: 304: 100.00
+	Hs
		435742 IGF1R_HUMAN (347-885): 2.31e-146: 474: 27.31		NTPCR_HUMAN (1-190): 2.26e-106: 304: 100.00
+	Hs
		601580 FGFR2_HUMAN (392-932): 6.72e-145: 455: 22.69		NTPCR_HUMAN (1-190): 2.26e-106: 304: 100.00