HitPredict

Interactor 1: EPHB2 (P29323)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: BI2L1 (Q9UHR4)
BAR/IMD domain-containing adapter protein 2-like 1 (Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1) (BAI1-associated protein 2-like protein 1) (Insulin receptor tyrosine kinase substrate)
Gene: BAIAP2L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1055 Hs			1 511
+	Hs
		665684 EPHB2_HUMAN (20-1055): 0: 1304: 100.00		BAIP2_HUMAN (6-505): 1.42e-118: 361: 39.55
+	Hs
		1072622 EPHA7_HUMAN (6-982): 0: 1154: 57.46		BI2L1_HUMAN (1-511): 8.22e-169: 488: 100.00
+	Hs
		872725 EPHA4_HUMAN (6-982): 0: 1152: 58.33		BI2L1_HUMAN (1-511): 8.22e-169: 488: 100.00
+	Hs
		665683 EPHB2_HUMAN (20-1055): 0: 1304: 100.00		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		1072630 EPHA7_HUMAN (6-982): 0: 1154: 57.46		BAIP2_HUMAN (6-505): 1.42e-118: 361: 39.55
+	Hs
		872731 EPHA4_HUMAN (6-982): 0: 1152: 58.33		BAIP2_HUMAN (6-505): 1.42e-118: 361: 39.55
+	Hs
		600697 EPHA1_HUMAN (12-976): 0: 961: 41.21		BI2L1_HUMAN (1-511): 8.22e-169: 488: 100.00
+	Hs
		1072628 EPHA7_HUMAN (6-982): 0: 1154: 57.46		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		872730 EPHA4_HUMAN (6-982): 0: 1152: 58.33		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		665608 EPHB2_HUMAN (20-1055): 0: 1304: 100.00		ITSN1_HUMAN (6-491): 1.88e-27: 119: 11.80
+	Hs
		872506 EPHA5_HUMAN (6-984): 0: 1148: 56.69		PACN2_HUMAN (8-401): 3.83e-86: 275: 13.07
+	Hs
		1072529 EPHA7_HUMAN (6-982): 0: 1154: 57.46		MTSS2_HUMAN (18-334): 2.74e-53: 194: 14.37
+	Rn
		544832 INSR_RAT (280-937): 2.81e-145: 471: 24.56		BI2L1_RAT (1-511): 1.51e-157: 459: 86.82
+	Hs
		674567 UFO_HUMAN (266-950): 2.71e-152: 477: 23.12		BAIP2_HUMAN (6-505): 1.42e-118: 361: 39.55
+	Hs
		601605 FGFR2_HUMAN (392-932): 6.72e-145: 455: 22.69		ITSN2_HUMAN (225-399): 4.87e-10: 64.6: 14.29