HitPredict

Interactor 1: EPHB2 (P29323)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Developmentally-regulated Eph-related tyrosine kinase) (ELK-related tyrosine kinase) (EPH tyrosine kinase 3) (EPH-like kinase 5) (EK5) (hEK5) (Renal carcinoma antigen NY-REN-47) (Tyrosine-protein kinase TYRO5) (Tyrosine-protein kinase receptor EPH-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: BAIP2 (Q9UQB8)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
Gene: BAIAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0043025 - neuronal cell body GO:0061003 - positive regulation of dendritic spine morphogenesis and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1055 Hs			1 552
+	Hs
		665679 EPHB2_HUMAN (20-1055): 0: 1304: 100.00		BI2L1_HUMAN (3-529): 1.57e-106: 330: 39.85
+	Hs
		1072630 EPHA7_HUMAN (6-982): 0: 1154: 57.46		BAIP2_HUMAN (1-552): 7.45e-143: 425: 100.00
+	Hs
		872731 EPHA4_HUMAN (6-982): 0: 1152: 58.33		BAIP2_HUMAN (1-552): 7.45e-143: 425: 100.00
+	Hs
		665683 EPHB2_HUMAN (20-1055): 0: 1304: 100.00		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		1072622 EPHA7_HUMAN (6-982): 0: 1154: 57.46		BI2L1_HUMAN (3-529): 1.57e-106: 330: 39.85
+	Hs
		872725 EPHA4_HUMAN (6-982): 0: 1152: 58.33		BI2L1_HUMAN (3-529): 1.57e-106: 330: 39.85
+	Hs
		665608 EPHB2_HUMAN (20-1055): 0: 1304: 100.00		ITSN1_HUMAN (268-455): 5.42e-10: 64.5: 15.18
+	Hs
		1072628 EPHA7_HUMAN (6-982): 0: 1154: 57.46		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		872730 EPHA4_HUMAN (6-982): 0: 1152: 58.33		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		872506 EPHA5_HUMAN (6-984): 0: 1148: 56.69		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		1072529 EPHA7_HUMAN (6-982): 0: 1154: 57.46		MTSS2_HUMAN (19-388): 2.46e-43: 166: 16.45
+	Hs
		600697 EPHA1_HUMAN (12-976): 0: 961: 41.21		BI2L1_HUMAN (3-529): 1.57e-106: 330: 39.85
+	Hs
		674567 UFO_HUMAN (266-950): 2.71e-152: 477: 23.12		BAIP2_HUMAN (1-552): 7.45e-143: 425: 100.00
+	Rn
		544832 INSR_RAT (280-937): 2.81e-145: 471: 24.56		BI2L1_RAT (3-529): 5.67e-102: 319: 38.39
+	Hs
		601605 FGFR2_HUMAN (392-932): 6.72e-145: 455: 22.69		ITSN2_HUMAN (166-444): 7.54e-12: 70.6: 14.13
+	Hs
		433354 YES_HUMAN (572-881): 5.77e-65: 231: 42.95		LASP1_HUMAN (207-435): 2.59e-40: 148: 15.98