Interactor 1: PTN6 (P29350)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)
Gene: PTPN6

Interactor 2: STAT3 (P40763)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15870198
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, SH2~Y_phosphatase
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008285 - negative regulation of cell population proliferation
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 595
Hs

1 770
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024