HitPredict

Interactor 1: PTN6 (P29350)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)
Gene: PTPN6

Interactor 2: KI2L1 (P43626)
Killer cell immunoglobulin-like receptor 2DL1 (CD158 antigen-like family member A) (Natural killer-associated transcript 1) (NKAT-1) (p58 natural killer cell receptor clones CL-42/47.11) (p58 NK receptor CL-42/47.11) (p58.1 MHC class-I-specific NK receptor) (CD antigen CD158a)
Gene: KIR2DL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.537

Property	Details
Experiments	18574028, 8691146
Identification Methods	anti tag coimmunoprecipitation, coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 348
+	Hs
		665820 PTN6_HUMAN (1-595): 0: 628: 100.00		KI2L3_HUMAN (1-340): 3.49e-131: 379: 90.32
+	Hs
		665921 PTN6_HUMAN (1-595): 0: 628: 100.00		LIRB4_HUMAN (1-324): 5.2e-81: 255: 29.46
+	Mm
		665991 PTN6_MOUSE (1-595): 0: 611: 94.45		LRB4A_MOUSE (1-335): 1.93e-72: 229: 26.25
+	Hs
		665821 PTN6_HUMAN (1-595): 0: 628: 100.00		KI3L1_HUMAN (1-348): 8.24e-64: 210: 30.77
+	Hs
		616953 PTPRD_HUMAN (126-516): 3.18e-114: 376: 29.41		KI2L1_HUMAN (1-348): 1.19e-135: 391: 100.00
+	Hs
		665902 PTN6_HUMAN (1-595): 0: 628: 100.00		LAIR1_HUMAN (1-141): 4.25e-36: 134: 23.08
+	Mm
		665982 PTN6_MOUSE (1-595): 0: 611: 94.45		LIRB3_MOUSE (29-246): 6.27e-31: 125: 26.22
+	Hs
		252776 PTN6_HUMAN (1-595): 0: 628: 100.00		LIRB3_HUMAN (30-335): 5.08e-24: 104: 23.99
+	Hs
		532361 PTN6_HUMAN (1-595): 0: 628: 100.00		CEAM1_HUMAN (14-295): 1.08e-21: 97.6: 13.91
+	Hs
		665922 PTN6_HUMAN (1-595): 0: 628: 100.00		LIRB1_HUMAN (12-122): 6.45e-17: 83.7: 35.14
+	Hs
		665916 PTN6_HUMAN (1-595): 0: 628: 100.00		LIRB2_HUMAN (10-138): 1.23e-15: 79.9: 35.66
+	Mm
		665995 PTN6_MOUSE (1-595): 0: 611: 94.45		LAIR1_MOUSE (16-138): 4.78e-19: 87.2: 17.46
+	Hs
		665941 PTN6_HUMAN (1-595): 0: 628: 100.00		FCRL3_HUMAN (30-199): 2.62e-11: 66.6: 17.42
+	Mm
		665992 PTN6_MOUSE (1-595): 0: 611: 94.45		FCRL5_MOUSE (4-252): 1.64e-10: 64.1: 13.10
+	Hs
		616999 PTPRD_HUMAN (126-516): 3.18e-114: 376: 29.41		LIRB4_HUMAN (1-324): 5.2e-81: 255: 29.46
+	Hs
		798139 PTN11_HUMAN (2-203): 1.25e-24: 110: 25.23		KI2L1_HUMAN (1-348): 1.19e-135: 391: 100.00
+	Hs
		798184 PTN11_HUMAN (2-203): 1.25e-24: 110: 25.23		KI2L3_HUMAN (1-340): 3.49e-131: 379: 90.32
+	Mm
		682309 PTN12_MOUSE (218-575): 3.21e-115: 362: 32.42		CEAM1_MOUSE (30-338): 2.34e-20: 93.8: 13.98
+	Hs
		798232 PTN11_HUMAN (2-203): 1.25e-24: 110: 25.23		KI3L1_HUMAN (1-348): 8.24e-64: 210: 30.77
+	Hs
		532367 PTN11_HUMAN (2-203): 1.25e-24: 110: 25.23		CEAM1_HUMAN (14-295): 1.08e-21: 97.6: 13.91