Interactor 1: PTN6 (P29350)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)
Gene: PTPN6

Interactor 2: PTN12 (Q05209)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)
Gene: PTPN12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 28514442, 27432908, 31980649, 33961781, unassigned2173
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~Y_phosphatase, Y_phosphatase~Y_phosphatase
Common GO terms GO:0004725 - protein tyrosine phosphatase activity
GO:0004726 - non-membrane spanning protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 4 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 595
Hs

1 780
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Last updated: 15 Jul 2024