HitPredict

Interactor 1: PTN6 (P29351)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (70Z-SHP) (Hematopoietic cell protein-tyrosine phosphatase) (PTPTY-42) (Protein-tyrosine phosphatase 1C) (PTP-1C) (SH-PTP1) (SHP-1)
Gene: Ptpn6

Interactor 2: CD22 (P35329)
B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)
Gene: CD22

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.50	0.504

Property	Details
Experiments	9890995, 11551923
Identification Methods	coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 595 Mm			1 868
+	Hs
		590601 PTN6_HUMAN (1-595): 0: 639: 94.45		CD22_HUMAN (19-868): 1.88e-168: 512: 58.73
+	Hs
		665883 PTN6_HUMAN (1-595): 0: 639: 94.45		PTK7_HUMAN (19-795): 5.66e-90: 309: 15.11
+	Hs
		441175 PTPRC_HUMAN (31-591): 5.08e-93: 313: 18.42		CD22_HUMAN (19-868): 1.88e-168: 512: 58.73
+	Hs
		665942 PTN6_HUMAN (1-595): 0: 639: 94.45		SIG11_HUMAN (395-771): 2.98e-41: 163: 22.38
+	Hs
		665940 PTN6_HUMAN (1-595): 0: 639: 94.45		SIG10_HUMAN (314-867): 8.2e-36: 147: 19.50
+	Gg
		47583 A0A8V0YWD3_CHICK (31-516): 1.3e-123: 387: 23.02		CNTN1_CHICK (47-796): 3.8e-53: 202: 12.39
+	Hs
		131993 PTPRA_HUMAN (31-516): 8.4e-124: 385: 22.47		NCHL1_HUMAN (31-803): 4.08e-51: 197: 12.56
+	Mm
		574004 PTPRA_MOUSE (31-516): 7.64e-124: 386: 22.27		NCHL1_MOUSE (31-713): 3.68e-50: 194: 13.35
+	Hs
		581462 PTN4_HUMAN (78-530): 1.31e-125: 393: 26.43		VCAM1_HUMAN (443-789): 1.66e-29: 127: 19.27
+	Mm
		530202 PTPRA_MOUSE (31-516): 7.64e-124: 386: 22.27		NCAM1_MOUSE (80-432): 3.4e-11: 69.5: 15.03
+	Hs
		985950 PTN11_HUMAN (2-243): 3.45e-26: 114: 22.99		PTK7_HUMAN (19-795): 5.66e-90: 309: 15.11
+	Hs
		617163 PTPRZ_HUMAN (34-529): 1.34e-73: 258: 18.44		CNTN1_HUMAN (71-679): 4.11e-34: 143: 12.03
+	Hs
		616927 PTPRB_HUMAN (268-524): 2.77e-50: 189: 39.54		NRCAM_HUMAN (18-818): 3.32e-42: 169: 12.02
+	Hs
		1069952 PTPRK_HUMAN (33-519): 8.08e-79: 273: 18.24		PXDN_HUMAN (257-599): 1.01e-15: 84.3: 27.35
+	Hs
		616914 PTPRB_HUMAN (268-524): 2.77e-50: 189: 39.54		CNTN1_HUMAN (71-679): 4.11e-34: 143: 12.03
+	Hs
		986018 PTN11_HUMAN (2-243): 3.45e-26: 114: 22.99		SIG11_HUMAN (395-771): 2.98e-41: 163: 22.38
+	Hs
		986013 PTN11_HUMAN (2-243): 3.45e-26: 114: 22.99		SIG10_HUMAN (314-867): 8.2e-36: 147: 19.50
+	Mm
		719313 PTN11_MOUSE (2-243): 3.84e-26: 114: 22.99		SIG10_MOUSE (307-846): 9.4e-34: 140: 18.35
+	Hs
		581691 PTN11_HUMAN (2-243): 3.45e-26: 114: 22.99		VCAM1_HUMAN (443-789): 1.66e-29: 127: 19.27