HitPredict

Interactor 1: PTN6 (P29351)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (70Z-SHP) (Hematopoietic cell protein-tyrosine phosphatase) (PTPTY-42) (Protein-tyrosine phosphatase 1C) (PTP-1C) (SH-PTP1) (SHP-1)
Gene: Ptpn6

Interactor 2: LAIR1 (Q8BG84)
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) (mLAIR1) (CD antigen CD305)
Gene: LAIR1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	25915125
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Mm			1 263
+	Hs
		665902 PTN6_HUMAN (1-595): 0: 639: 94.45		LAIR1_HUMAN (1-263): 1.01e-80: 246: 39.72
+	Hs
		665921 PTN6_HUMAN (1-595): 0: 639: 94.45		LIRB4_HUMAN (1-263): 8.21e-55: 184: 20.66
+	Mm
		665991 PTN6_MOUSE (1-595): 0: 634: 100.00		LRB4A_MOUSE (4-246): 3.46e-32: 122: 13.46
+	Hs
		665820 PTN6_HUMAN (1-595): 0: 639: 94.45		KI2L3_HUMAN (1-136): 9.56e-30: 116: 18.06
+	Hs
		665821 PTN6_HUMAN (1-595): 0: 639: 94.45		KI3L1_HUMAN (1-135): 1.81e-27: 111: 19.72
+	Hs
		665819 PTN6_HUMAN (1-595): 0: 639: 94.45		KI2L1_HUMAN (1-143): 6.81e-24: 100: 15.89
+	Hs
		665916 PTN6_HUMAN (1-595): 0: 639: 94.45		LIRB2_HUMAN (24-135): 3.98e-20: 91.4: 16.67
+	Hs
		665922 PTN6_HUMAN (1-595): 0: 639: 94.45		LIRB1_HUMAN (1-144): 3.5e-20: 91.4: 13.42
+	Hs
		252776 PTN6_HUMAN (1-595): 0: 639: 94.45		LIRB3_HUMAN (22-144): 1.22e-18: 86.8: 17.83
+	Mm
		665982 PTN6_MOUSE (1-595): 0: 634: 100.00		LIRB3_MOUSE (29-154): 7.25e-15: 76: 17.29
+	Hs
		616999 PTPRD_HUMAN (34-516): 1.72e-125: 408: 25.00		LIRB4_HUMAN (1-263): 8.21e-55: 184: 20.66
+	Hs
		616953 PTPRD_HUMAN (34-516): 1.72e-125: 408: 25.00		KI2L1_HUMAN (1-143): 6.81e-24: 100: 15.89
+	Hs
		985972 PTN11_HUMAN (2-243): 3.45e-26: 114: 22.99		LAIR1_HUMAN (1-263): 1.01e-80: 246: 39.72
+	Mm
		719307 PTN11_MOUSE (2-243): 3.84e-26: 114: 22.99		LRB4A_MOUSE (4-246): 3.46e-32: 122: 13.46
+	Hs
		986023 PTN11_HUMAN (2-243): 3.45e-26: 114: 22.99		KI2L4_HUMAN (1-143): 4.85e-30: 117: 25.68
+	Hs
		798184 PTN11_HUMAN (2-243): 3.45e-26: 114: 22.99		KI2L3_HUMAN (1-136): 9.56e-30: 116: 18.06
+	Hs
		798232 PTN11_HUMAN (2-243): 3.45e-26: 114: 22.99		KI3L1_HUMAN (1-135): 1.81e-27: 111: 19.72
+	Hs
		798139 PTN11_HUMAN (2-243): 3.45e-26: 114: 22.99		KI2L1_HUMAN (1-143): 6.81e-24: 100: 15.89
+	Mm
		719293 PTN11_MOUSE (2-243): 3.84e-26: 114: 22.99		LIRB3_MOUSE (29-154): 7.25e-15: 76: 17.29
+	Mm
		719316 PTN11_MOUSE (2-243): 3.84e-26: 114: 22.99		Q8K4V6_MOUSE (23-154): 1.23e-12: 69.4: 17.73