HitPredict

Interactor 1: PTN22 (P29352)
Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (PEST-domain phosphatase) (PEP)
Gene: Ptpn22

Interactor 2: PPIP1 (P97814)
Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1)
Gene: Pstpip1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9804817
Identification Methods	competition binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 802 Mm			1 415
+	Hs
		207851 PTN22_HUMAN (1-802): 0: 1065: 70.53		PPIP1_HUMAN (1-415): 1.14e-81: 258: 87.98
+	Mm
		666001 PTN22_MOUSE (1-802): 0: 1127: 100.00		PPIP2_MOUSE (2-310): 2.61e-53: 182: 43.55
+	Hs
		1333999 PTN22_HUMAN (1-802): 0: 1065: 70.53		PPIP2_HUMAN (2-334): 5.58e-53: 181: 41.62
+	Hs
		1078935 PTN22_HUMAN (1-802): 0: 1065: 70.53		ITSN1_HUMAN (311-414): 1.25e-09: 62.5: 15.39
+	Hs
		207795 PTN12_HUMAN (1-800): 0: 840: 34.49		PPIP1_HUMAN (1-415): 1.14e-81: 258: 87.98
+	Mm
		728826 PTN12_MOUSE (1-800): 0: 812: 35.03		PPIP1_MOUSE (1-415): 3.71e-81: 257: 100.00
+	Hs
		983514 PTN12_HUMAN (1-800): 0: 840: 34.49		PPIP2_HUMAN (2-334): 5.58e-53: 181: 41.62
+	Mm
		728830 PTN12_MOUSE (1-800): 0: 812: 35.03		PPIP2_MOUSE (2-310): 2.61e-53: 182: 43.55
+	Hs
		207829 PTN18_HUMAN (3-349): 6.32e-131: 399: 40.12		PPIP1_HUMAN (1-415): 1.14e-81: 258: 87.98
+	Mm
		956955 PTN18_MOUSE (3-333): 3.7e-129: 394: 41.74		PPIP1_MOUSE (1-415): 3.71e-81: 257: 100.00
+	Hs
		1307332 PTN18_HUMAN (3-349): 6.32e-131: 399: 40.12		PPIP2_HUMAN (2-334): 5.58e-53: 181: 41.62
+	Mm
		1142213 PTN18_MOUSE (3-333): 3.7e-129: 394: 41.74		PPIP2_MOUSE (2-310): 2.61e-53: 182: 43.55
+	Mm
		719322 PTN11_MOUSE (2-320): 7.38e-125: 388: 31.66		ITSN1_MOUSE (311-414): 5.11e-10: 63.6: 14.42
+	Hs
		207769 PTN1_HUMAN (34-288): 1.4e-42: 162: 36.40		PPIP1_HUMAN (1-415): 1.14e-81: 258: 87.98
+	Hs
		617105 PTPRG_HUMAN (20-295): 7.88e-53: 201: 24.13		FCHO2_HUMAN (2-384): 5.97e-51: 185: 19.00