Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: TGFR2 (P37173)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: TGFBR2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 17440088
Identification Methods coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007507 - heart development
GO:0008284 - positive regulation of cell population proliferation
GO:0071363 - cellular response to growth factor stimulus
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 583
Hs

1 567
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024