Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: SOS1 (Q07889)
Son of sevenless homolog 1 (SOS-1)
Gene: SOS1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 16371368, 7559490, 8621459, 8626525, 8235613, 9344843, 19380743, 10675333, 10783152, 10570290, 10025673, 8950973, 9544989
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005154 - epidermal growth factor receptor binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0008286 - insulin receptor signaling pathway
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 583
Hs

1 1333
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Last updated: 15 Jul 2024