HitPredict

Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 583 Hs			1 450
+	Hs
		428036 SHC1_HUMAN (1-583): 0: 531: 100.00		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		666064 SHC1_HUMAN (1-583): 0: 531: 100.00		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		666166 SHC1_HUMAN (1-583): 0: 531: 100.00		TBB2B_HUMAN (1-430): 0: 703: 93.72
+	Hs
		666165 SHC1_HUMAN (1-583): 0: 531: 100.00		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		548704 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		428001 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		548681 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		381112 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Mm
		958399 ANS1B_MOUSE (39-364): 1.02e-45: 175: 17.86		TBB5_MOUSE (1-429): 0: 704: 93.94
+	Mm
		1206676 ANS1B_MOUSE (39-364): 1.02e-45: 175: 17.86		TBB2B_MOUSE (1-430): 0: 703: 93.72
+	Mm
		934055 ANS1B_MOUSE (39-364): 1.02e-45: 175: 17.86		TBB4B_MOUSE (1-427): 0: 703: 93.91
+	Mm
		1186466 ANS1B_MOUSE (39-364): 1.02e-45: 175: 17.86		TBB2A_MOUSE (1-430): 0: 700: 93.49
+	Hs
		129166 P85B_HUMAN (358-581): 2.69e-29: 125: 17.47		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		129330 P85B_HUMAN (358-581): 2.69e-29: 125: 17.47		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		924548 GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		428131 GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		924460 GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		924836 GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Dm
		665785 CSW_DROME (483-579): 2.71e-12: 71.8: 27.72		Q8MST5_DROME (1-448): 0: 705: 86.61