HitPredict

Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: SCLT1 (Q96NL6)
Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1)
Gene: SCLT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 583 Hs			1 688
+	Hs
		666020 SHC1_HUMAN (1-583): 0: 531: 100.00		MYH11_HUMAN (1-345): 1.26e-12: 73.8: 11.86
+	Hs
		666019 SHC1_HUMAN (1-583): 0: 531: 100.00		MYH10_HUMAN (350-686): 3.14e-11: 69.2: 11.70
+	Hs
		666018 SHC1_HUMAN (1-583): 0: 531: 100.00		MYH9_HUMAN (311-686): 8.81e-11: 67.7: 10.91
+	Hs
		522633 SHD_HUMAN (328-582): 1.62e-47: 171: 23.02		MYH7_HUMAN (1-566): 2.05e-23: 108: 10.79
+	Hs
		1068630 Q96D37_HUMAN (163-578): 1.11e-54: 200: 12.25		PLEC_HUMAN (74-659): 3.28e-10: 66: 20.48
+	Hs
		548710 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		PLEC_HUMAN (74-659): 3.28e-10: 66: 20.48
+	Hs
		551599 NCK1_HUMAN (360-575): 1.55e-41: 155: 18.30		DESP_HUMAN (1-661): 7.45e-20: 97.1: 14.39
+	Hs
		426943 FES_HUMAN (326-581): 1.46e-37: 150: 21.79		DESP_HUMAN (1-661): 7.45e-20: 97.1: 14.39
+	Hs
		528420 SHD_HUMAN (328-582): 1.62e-47: 171: 23.02		MYH8_HUMAN (350-685): 2.47e-11: 69.6: 10.85
+	Hs
		275589 BCAR3_HUMAN (379-583): 3.82e-38: 152: 23.83		MY18A_HUMAN (82-659): 3.07e-13: 75.6: 21.14
+	Hs
		426959 FES_HUMAN (326-581): 1.46e-37: 150: 21.79		PLEC_HUMAN (74-659): 3.28e-10: 66: 20.48
+	Hs
		129221 P85B_HUMAN (358-581): 2.69e-29: 125: 17.47		MYH10_HUMAN (350-686): 3.14e-11: 69.2: 11.70
+	Hs
		129220 P85B_HUMAN (358-581): 2.69e-29: 125: 17.47		MYH9_HUMAN (311-686): 8.81e-11: 67.7: 10.91
+	Hs
		924736 GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48		MY18A_HUMAN (82-659): 3.07e-13: 75.6: 21.14
+	Hs
		728465 GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48		MYH11_HUMAN (1-345): 1.26e-12: 73.8: 11.86
+	Hs
		725134 GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48		MYH10_HUMAN (350-686): 3.14e-11: 69.2: 11.70
+	Hs
		724756 GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48		MYH9_HUMAN (311-686): 8.81e-11: 67.7: 10.91
+	Hs
		924586 GRB2_HUMAN (482-578): 1.65e-15: 77.5: 30.48		PLEC_HUMAN (74-659): 3.28e-10: 66: 20.48