HitPredict

Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: ARAP1 (Q96P48)
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2)
Gene: ARAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 583 Hs			1 1450
+	Hs
		209145 NCK2_HUMAN (363-579): 5.31e-45: 165: 18.83		ARAP1_HUMAN (1-1450): 0: 1074: 100.00
+	Hs
		557775 NCK1_HUMAN (360-575): 1.55e-41: 155: 18.30		ARAP1_HUMAN (1-1450): 0: 1074: 100.00
+	Hs
		1262747 ANS1A_HUMAN (40-393): 2.28e-42: 165: 18.41		ARAP3_HUMAN (4-1430): 0: 788: 32.76
+	Hs
		64661 SHC1_HUMAN (1-583): 0: 531: 100.00		RHG32_HUMAN (647-1331): 2.29e-86: 314: 16.71
+	Hs
		64726 SHC3_HUMAN (6-582): 3.32e-127: 387: 45.47		RHG32_HUMAN (647-1331): 2.29e-86: 314: 16.71
+	Hs
		64693 SHC2_HUMAN (56-582): 4.56e-116: 358: 44.88		RHG32_HUMAN (647-1331): 2.29e-86: 314: 16.71
+	Hs
		64627 NCK2_HUMAN (363-579): 5.31e-45: 165: 18.83		RHG32_HUMAN (647-1331): 2.29e-86: 314: 16.71
+	Hs
		561401 FER_HUMAN (345-581): 6.27e-42: 163: 18.75		RHG23_HUMAN (677-1150): 5.65e-87: 314: 22.79
+	Hs
		64651 NCK1_HUMAN (360-575): 1.55e-41: 155: 18.30		RHG32_HUMAN (647-1331): 2.29e-86: 314: 16.71
+	Mm
		1112613 ANS1B_MOUSE (39-364): 1.02e-45: 175: 17.86		AGAP2_MOUSE (277-760): 5.12e-81: 293: 17.25
+	Hs
		64658 P85A_HUMAN (300-581): 2.38e-38: 152: 15.31		RHG32_HUMAN (647-1331): 2.29e-86: 314: 16.71
+	Hs
		195770 NCK2_HUMAN (363-579): 5.31e-45: 165: 18.83		ASAP2_HUMAN (322-766): 7.55e-83: 296: 19.59
+	Hs
		655450 P85A_HUMAN (300-581): 2.38e-38: 152: 15.31		AGAP2_HUMAN (277-760): 7.44e-84: 302: 18.32
+	Hs
		195783 NCK1_HUMAN (360-575): 1.55e-41: 155: 18.30		ASAP2_HUMAN (322-766): 7.55e-83: 296: 19.59
+	Hs
		195787 P85A_HUMAN (300-581): 2.38e-38: 152: 15.31		ASAP2_HUMAN (322-766): 7.55e-83: 296: 19.59
+	Hs
		208987 NCK2_HUMAN (363-579): 5.31e-45: 165: 18.83		CHIN_HUMAN (845-1139): 1.19e-70: 247: 22.37
+	Hs
		551038 NCK1_HUMAN (360-575): 1.55e-41: 155: 18.30		CHIN_HUMAN (845-1139): 1.19e-70: 247: 22.37
+	Hs
		561393 FER_HUMAN (345-581): 6.27e-42: 163: 18.75		RHG21_HUMAN (84-499): 2.61e-25: 116: 10.45
+	Hs
		557714 NCK1_HUMAN (360-575): 1.55e-41: 155: 18.30		RHG21_HUMAN (84-499): 2.61e-25: 116: 10.45
+	Hs
		1191814 ANS1B_HUMAN (39-351): 1.55e-45: 175: 17.96		RHG26_HUMAN (926-1140): 1.18e-16: 87.8: 27.83