Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1
Interactor 2: GARE1 (Q9H706)
GRB2-associated and regulator of MAPK protein 1 (GRB2-associated and regulator of MAPK1)
Gene: GAREM1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 0.60 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 31980649, 33961781, unassigned2173 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005886 - plasma membrane GO:0007173 - epidermal growth factor receptor signaling pathway GO:0008284 - positive regulation of cell population proliferation GO:0070374 - positive regulation of ERK1 and ERK2 cascade |
| Homologous interactions | 6 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
