HitPredict

Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: TBA8 (Q9NY65)
Tubulin alpha-8 chain (EC 3.6.5.-) (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Cleaved into: Dephenylalaninated tubulin alpha-8 chain]
Gene: TUBA8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 583 Hs			1 449
+	Hs
		666163 SHC1_HUMAN (1-583): 0: 531: 100.00		TBA1C_HUMAN (1-449): 0: 717: 89.76
+	Hs
		666063 SHC1_HUMAN (1-583): 0: 531: 100.00		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Mm
		933697 SHC1_MOUSE (1-583): 0: 527: 94.51		TBA4A_MOUSE (1-448): 0: 710: 89.96
+	Hs
		666131 SHC1_HUMAN (1-583): 0: 531: 100.00		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Hs
		428036 SHC1_HUMAN (1-583): 0: 531: 100.00		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		666064 SHC1_HUMAN (1-583): 0: 531: 100.00		TBB4B_HUMAN (1-437): 0: 691: 39.13
+	Hs
		548680 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		548729 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Hs
		428001 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		548725 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		TBA3E_HUMAN (1-439): 0: 693: 90.43
+	Hs
		548681 VAV_HUMAN (163-578): 1.81e-54: 200: 12.25		TBB4B_HUMAN (1-437): 0: 691: 39.13
+	Mm
		958399 ANS1B_MOUSE (39-364): 1.02e-45: 175: 17.86		TBB5_MOUSE (1-439): 0: 694: 39.41
+	Hs
		933524 SH2D3_HUMAN (333-582): 8.25e-40: 157: 23.55		TBA4A_HUMAN (1-448): 0: 710: 89.96
+	Mm
		57446 A2AM67_MOUSE (191-575): 2.18e-43: 162: 14.47		TBA1A_MOUSE (1-439): 0: 704: 90.89
+	Mm
		934055 ANS1B_MOUSE (39-364): 1.02e-45: 175: 17.86		TBB4B_MOUSE (1-437): 0: 691: 39.13
+	Hs
		557723 NCK1_HUMAN (360-575): 1.55e-41: 155: 18.30		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Hs
		655312 P85A_HUMAN (300-581): 2.38e-38: 152: 15.31		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		129329 P85B_HUMAN (358-581): 2.69e-29: 125: 17.47		TBA1C_HUMAN (1-449): 0: 717: 89.76
+	Hs
		129166 P85B_HUMAN (358-581): 2.69e-29: 125: 17.47		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		1175137 SH23A_HUMAN (475-581): 3.64e-17: 86.8: 33.06		TBA1A_HUMAN (1-439): 0: 704: 90.89