HitPredict

Interactor 1: SEM5 (P29355)
Sex muscle abnormal protein 5
Gene: sem-5

Interactor 2: UNC53 (Q7YSI9)
Adapter protein unc-53 (Uncoordinated protein 53)
Gene: unc-53

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12091307
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 228 Ce			1 1654
+	Hs
		411792 LCK_HUMAN (138-228): 4.97e-12: 66.5: 18.28		NAV1_HUMAN (268-1632): 8.96e-149: 504: 17.74
+	Hs
		924482 GRB2_HUMAN (1-214): 5.56e-66: 204: 57.60		SPTB2_HUMAN (4-244): 2.29e-55: 215: 17.28
+	Hs
		211557 GRB2_HUMAN (1-214): 5.56e-66: 204: 57.60		ACTN4_HUMAN (5-253): 1.99e-50: 196: 13.15
+	Hs
		924586 GRB2_HUMAN (1-214): 5.56e-66: 204: 57.60		PLEC_HUMAN (8-253): 8e-26: 119: 14.92
+	Hs
		963335 ITSN1_HUMAN (110-222): 1.4e-13: 71.5: 19.17		SPTB2_HUMAN (4-244): 2.29e-55: 215: 17.28
+	Hs
		924484 GRB2_HUMAN (1-214): 5.56e-66: 204: 57.60		ANK2_HUMAN (178-891): 1.6e-13: 78.5: 12.12
+	Hs
		411676 LCK_HUMAN (138-228): 4.97e-12: 66.5: 18.28		SPTB2_HUMAN (4-244): 2.29e-55: 215: 17.28
+	Hs
		1078871 ITSN1_HUMAN (110-222): 1.4e-13: 71.5: 19.17		SYNE1_HUMAN (4-244): 1.33e-52: 207: 12.26
+	Hs
		211480 SRC_HUMAN (57-226): 3.34e-16: 78.9: 16.28		ACTN4_HUMAN (5-253): 1.99e-50: 196: 13.15
+	Hs
		433543 LYN_HUMAN (89-212): 1.12e-10: 62.5: 21.43		DMD_HUMAN (4-344): 2.43e-54: 212: 12.25
+	Hs
		164551 LCK_HUMAN (138-228): 4.97e-12: 66.5: 18.28		SPTN2_HUMAN (4-244): 1.16e-52: 206: 16.05
+	Hs
		411637 LCK_HUMAN (138-228): 4.97e-12: 66.5: 18.28		UTRN_HUMAN (5-295): 1.9e-51: 203: 13.36
+	Hs
		164555 LYN_HUMAN (89-212): 1.12e-10: 62.5: 21.43		SPTN2_HUMAN (4-244): 1.16e-52: 206: 16.05
+	Hs
		211443 SRBS2_HUMAN (37-222): 2.01e-12: 68.1: 18.52		ACTN4_HUMAN (5-253): 1.99e-50: 196: 13.15
+	Hs
		297808 LYN_HUMAN (89-212): 1.12e-10: 62.5: 21.43		K0754_HUMAN (77-687): 1.59e-35: 151: 8.18
+	Dm
		1360792 Q9VA36_DROME (155-218): 4.51e-12: 66.9: 25.76		FLNA_DROME (8-655): 1.2e-31: 138: 13.66
+	Hs
		1068630 Q96D37_HUMAN (2-60): 2.25e-14: 73.4: 35.59		PLEC_HUMAN (8-253): 8e-26: 119: 14.92
+	Hs
		548710 VAV_HUMAN (2-60): 2.95e-14: 73.1: 35.59		PLEC_HUMAN (8-253): 8e-26: 119: 14.92
+	Ce
		136804 VAV_CAEEL (55-212): 1.6e-19: 88.6: 33.93		UNC89_CAEEL (415-1120): 2.04e-12: 75: 12.89
+	Hs
		412362 FYN_HUMAN (159-228): 3.6e-18: 84.6: 25.00		MAGE1_HUMAN (359-793): 1.92e-10: 68.1: 13.78