HitPredict

Interactor 1: SEM5 (P29355)
Sex muscle abnormal protein 5
Gene: sem-5

Interactor 2: Q93203 (Q93203)
ANK_REP_REGION domain-containing protein
Gene: C11E4.6

Species: Caenorhabditis elegans

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.80	0.757

Property	Details
Experiments	12679813, 10615043, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 228 Ce			1 1170
+	Ce
		220231 SRC2_CAEEL (114-228): 2.45e-17: 81.9: 21.37		Q93203_CAEEL (1-1170): 0: 773: 100.00
+	Hs
		1268522 CD2AP_HUMAN (1-221): 1.54e-33: 128: 17.20		ANS1A_HUMAN (10-1168): 3.56e-143: 463: 15.54
+	Hs
		1268487 SH3K1_HUMAN (3-170): 5.8e-15: 75.4: 14.20		ANS1A_HUMAN (10-1168): 3.56e-143: 463: 15.54
+	Hs
		1191815 CD2AP_HUMAN (1-221): 1.54e-33: 128: 17.20		ANS1B_HUMAN (1-1010): 9.21e-96: 335: 16.46
+	Hs
		924484 GRB2_HUMAN (1-214): 5.56e-66: 204: 57.60		ANK2_HUMAN (13-440): 9.06e-54: 209: 16.12
+	Mm
		1206702 ITSN1_MOUSE (53-222): 2.31e-16: 79.6: 15.61		ANS1B_MOUSE (1-1010): 3.44e-92: 324: 15.02
+	Hs
		1115812 SH3K1_HUMAN (3-170): 5.8e-15: 75.4: 14.20		Q49AR9_HUMAN (820-1168): 5.01e-94: 314: 18.01
+	Hs
		433701 LYN_HUMAN (89-212): 1.12e-10: 62.5: 21.43		ANK2_HUMAN (13-440): 9.06e-54: 209: 16.12
+	Hs
		924794 GRB2_HUMAN (1-214): 5.56e-66: 204: 57.60		EHMT2_HUMAN (72-286): 1.4e-09: 64.7: 28.57
+	Hs
		64307 ITSN1_HUMAN (110-222): 1.4e-13: 71.5: 19.17		AN36A_HUMAN (4-1063): 3.59e-46: 184: 10.34
+	Hs
		411885 LCK_HUMAN (138-228): 4.97e-12: 66.5: 18.28		KDIS_HUMAN (1-245): 1.42e-40: 166: 14.69
+	Hs
		434071 LYN_HUMAN (89-212): 1.12e-10: 62.5: 21.43		KDIS_HUMAN (1-245): 1.42e-40: 166: 14.69
+	Hs
		1263386 SH3K1_HUMAN (3-170): 5.8e-15: 75.4: 14.20		CSKI2_HUMAN (9-208): 2.07e-30: 132: 17.73
+	Hs
		411806 LCK_HUMAN (138-228): 4.97e-12: 66.5: 18.28		CSKI2_HUMAN (9-208): 2.07e-30: 132: 17.73
+	Hs
		337406 ABL1_HUMAN (4-140): 3.2e-24: 102: 38.73		DAPK1_HUMAN (177-431): 3.65e-18: 93: 12.40
+	Hs
		433924 LYN_HUMAN (89-212): 1.12e-10: 62.5: 21.43		CSKI2_HUMAN (9-208): 2.07e-30: 132: 17.73
+	Hs
		1078859 ITSN1_HUMAN (110-222): 1.4e-13: 71.5: 19.17		MIB1_HUMAN (181-562): 2.2e-25: 116: 10.31
+	Hs
		411697 LCK_HUMAN (138-228): 4.97e-12: 66.5: 18.28		ANK3_HUMAN (1-153): 1.09e-20: 101: 16.34
+	Hs
		433730 LYN_HUMAN (89-212): 1.12e-10: 62.5: 21.43		ANK3_HUMAN (1-153): 1.09e-20: 101: 16.34
+	Hs
		257713 ITSN2_HUMAN (121-222): 1.75e-16: 80: 21.15		ANR17_HUMAN (5-137): 9.17e-15: 81.8: 14.29