HitPredict

Interactor 1: LTK (P29376)
Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)
Gene: LTK

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 1025
+	Hs
		666625 LTK_HUMAN (1-864): 0: 763: 100.00		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		601535 FGFR2_HUMAN (163-833): 6.48e-137: 429: 20.03		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Hs
		725069 ALK_HUMAN (4-851): 0: 701: 54.51		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		725268 ALK_HUMAN (4-851): 0: 701: 54.51		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		601553 FGFR2_HUMAN (163-833): 6.48e-137: 429: 20.03		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		600669 EPHA1_HUMAN (25-817): 9.44e-137: 433: 19.11		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		601589 FGFR2_HUMAN (163-833): 6.48e-137: 429: 20.03		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		609511 FGFR3_HUMAN (100-834): 2.96e-137: 429: 20.99		SCAPE_HUMAN (71-937): 4.97e-45: 179: 13.95
+	Hs
		508118 FGFR1_HUMAN (333-827): 2.64e-122: 390: 24.42		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		508190 FGFR1_HUMAN (333-827): 2.64e-122: 390: 24.42		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		600673 EPHA1_HUMAN (25-817): 9.44e-137: 433: 19.11		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		435765 IGF1R_HUMAN (298-854): 3.35e-128: 419: 27.39		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		600712 EPHA1_HUMAN (25-817): 9.44e-137: 433: 19.11		PKHA6_HUMAN (356-581): 1.69e-31: 135: 24.49
+	Hs
		665661 EPHB2_HUMAN (391-796): 1.67e-127: 410: 26.21		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		508062 FGFR1_HUMAN (333-827): 2.64e-122: 390: 24.42		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		872491 EPHA5_HUMAN (389-809): 8.73e-124: 400: 26.02		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		255286 EPHA1_HUMAN (25-817): 9.44e-137: 433: 19.11		HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56
+	Hs
		665375 EPHA3_HUMAN (388-798): 3.64e-124: 400: 27.30		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		254442 FGFR1_HUMAN (333-827): 2.64e-122: 390: 24.42		ROCK2_HUMAN (446-1018): 6.09e-17: 88.7: 11.81
+	Hs
		508011 FGFR1_HUMAN (333-827): 2.64e-122: 390: 24.42		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96