HitPredict

Interactor 1: GBB4 (P29387)
Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)
Gene: Gnb4

Interactor 2: GBG4 (P50153)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
Gene: Gng4

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	8636150
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	G-gamma~WD40
Common GO terms	GO:0003924 - GTPase activity GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Mm			1 75
+	Hs
		837673 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG4_HUMAN (1-75): 1.41e-30: 103: 98.67
+	Hs
		837682 GBB4_HUMAN (1-340): 5.89e-110: 325: 96.77		GBG4_HUMAN (1-75): 1.41e-30: 103: 98.67
+	Hs
		921516 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG3_HUMAN (1-75): 7.91e-30: 102: 68.00
+	Hs
		929157 GBB4_HUMAN (1-340): 5.89e-110: 325: 96.77		GBG3_HUMAN (1-75): 7.91e-30: 102: 68.00
+	Hs
		887097 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG2_HUMAN (5-75): 1.22e-28: 99: 76.06
+	Hs
		887126 GBB4_HUMAN (1-340): 5.89e-110: 325: 96.77		GBG2_HUMAN (5-75): 1.22e-28: 99: 76.06
+	Hs
		921771 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG8_HUMAN (7-75): 3.45e-25: 90.1: 59.42
+	Hs
		229238 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG7_HUMAN (8-75): 1.85e-24: 88.2: 61.77
+	Hs
		229245 GBB4_HUMAN (1-340): 5.89e-110: 325: 96.77		GBG7_HUMAN (8-75): 1.85e-24: 88.2: 61.77
+	Hs
		921761 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG12_HUMAN (7-75): 1.55e-23: 85.9: 55.07
+	Hs
		837687 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG10_HUMAN (8-75): 1.32e-21: 80.9: 47.06
+	Hs
		837704 GBB4_HUMAN (1-340): 5.89e-110: 325: 96.77		GBG10_HUMAN (8-75): 1.32e-21: 80.9: 47.06
+	Hs
		921517 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG5_HUMAN (8-75): 8.6e-21: 78.9: 44.12
+	Hs
		929176 GBB4_HUMAN (1-340): 5.89e-110: 325: 96.77		GBG5_HUMAN (8-75): 8.6e-21: 78.9: 44.12
+	Hs
		921515 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG1_HUMAN (15-74): 8.79e-19: 73.9: 36.67
+	Hs
		929139 Q6FHM2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBG1_HUMAN (15-74): 8.79e-19: 73.9: 36.67
+	Hs
		929145 GBB4_HUMAN (1-340): 5.89e-110: 325: 96.77		GBG1_HUMAN (15-74): 8.79e-19: 73.9: 36.67
+	Hs
		150115 GBB2_HUMAN (1-340): 2.47e-110: 326: 89.41		GBGT2_HUMAN (16-74): 1.31e-15: 65.8: 37.29
+	Hs
		150117 GBB4_HUMAN (1-340): 5.89e-110: 325: 96.77		GBGT2_HUMAN (16-74): 1.31e-15: 65.8: 37.29
+	Hs
		902497 GBB4_HUMAN (1-340): 5.89e-110: 325: 96.77		GBG11_HUMAN (14-74): 1.57e-15: 65.8: 36.07