HitPredict

Interactor 1: CALR (P29413)
Calreticulin
Gene: CALR

Interactor 2: PDIA6 (Q9V438)
Protein disulfide-isomerase A6 homolog (EC 5.3.4.1) (Calcium-binding protein 1) (DmCaBP1)
Gene: CaBP1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0012505 - endomembrane system
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Dm			1 433
+	Hs
		653597 CALR_HUMAN (21-361): 1.74e-163: 467: 71.72		PDIA6_HUMAN (1-433): 3.94e-119: 356: 57.66
+	Hs
		1067796 CALR3_HUMAN (11-361): 7.03e-154: 441: 43.06		PDIA6_HUMAN (1-433): 3.94e-119: 356: 57.66
+	Hs
		653711 CALR_HUMAN (21-361): 1.74e-163: 467: 71.72		ERP44_HUMAN (8-433): 1.78e-62: 208: 17.05
+	Hs
		1296643 CALR3_HUMAN (11-361): 7.03e-154: 441: 43.06		ERP44_HUMAN (8-433): 1.78e-62: 208: 17.05
+	Dm
		667013 CALR_DROME (1-406): 0: 545: 100.00		PDI_DROME (62-381): 7.85e-14: 74.9: 11.54
+	Hs
		531728 CALR_HUMAN (21-361): 1.74e-163: 467: 71.72		PDIA4_HUMAN (13-130): 4.76e-22: 100: 31.15
+	At
		137900 CALR1_ARATH (8-358): 5.31e-152: 438: 53.67		PDI21_ARATH (24-206): 1.87e-32: 128: 29.19
+	Hs
		653650 CALR_HUMAN (21-361): 1.74e-163: 467: 71.72		DJC10_HUMAN (25-377): 2.21e-20: 95.7: 17.60
+	Hs
		1055308 CALR3_HUMAN (11-361): 7.03e-154: 441: 43.06		PDIA5_HUMAN (68-415): 1.83e-28: 119: 18.31
+	Hs
		1240407 CALR3_HUMAN (11-361): 7.03e-154: 441: 43.06		TXND5_HUMAN (17-134): 1.24e-28: 118: 30.58
+	Hs
		653695 CALR_HUMAN (21-361): 1.74e-163: 467: 71.72		TMX3_HUMAN (1-127): 7.71e-17: 84.3: 36.15
+	Hs
		531950 CALR3_HUMAN (11-361): 7.03e-154: 441: 43.06		PDIA4_HUMAN (13-130): 4.76e-22: 100: 31.15
+	Hs
		653575 CALR_HUMAN (21-361): 1.74e-163: 467: 71.72		PDIA2_HUMAN (119-383): 7.48e-13: 72.2: 13.83
+	Hs
		1220455 CALR3_HUMAN (11-361): 7.03e-154: 441: 43.06		DJC10_HUMAN (25-377): 2.21e-20: 95.7: 17.60
+	Hs
		653491 CALR_HUMAN (21-361): 1.74e-163: 467: 71.72		PDIA3_HUMAN (21-382): 2.08e-09: 61.5: 11.58
+	Hs
		423330 CALR3_HUMAN (11-361): 7.03e-154: 441: 43.06		PDIA1_HUMAN (62-383): 4.03e-12: 69.9: 11.44
+	Hs
		671897 CALR3_HUMAN (11-361): 7.03e-154: 441: 43.06		PDIA3_HUMAN (21-382): 2.08e-09: 61.5: 11.58
+	Hs
		531729 CALX_HUMAN (18-353): 2.09e-129: 386: 34.42		PDIA4_HUMAN (13-130): 4.76e-22: 100: 31.15
+	Hs
		423150 CALX_HUMAN (18-353): 2.09e-129: 386: 34.42		PDIA1_HUMAN (62-383): 4.03e-12: 69.9: 11.44
+	Hs
		654099 CALX_HUMAN (18-353): 2.09e-129: 386: 34.42		PDIA3_HUMAN (21-382): 2.08e-09: 61.5: 11.58