Interactor 1: IL12B (P29460)
Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40) (NK cell stimulatory factor chain 2) (NKSF2)
Gene: IL12B
Interactor 2: I12R2 (Q99665)
Interleukin-12 receptor subunit beta-2 (IL-12 receptor subunit beta-2) (IL-12R subunit beta-2) (IL-12R-beta-2) (IL-12RB2)
Gene: IL12RB2
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8943050 |
| Identification Methods | competition binding |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL12p40_C~fn3 |
| Common GO terms | GO:0004896 - cytokine receptor activity GO:0009897 - external side of plasma membrane GO:0019221 - cytokine-mediated signaling pathway GO:0019955 - cytokine binding GO:0032729 - positive regulation of type II interferon production and 2 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
