Interactor 1: IL12B (P29460)
Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40) (NK cell stimulatory factor chain 2) (NKSF2)
Gene: IL12B
Interactor 2: IL23A (Q9NPF7)
Interleukin-23 subunit alpha (IL-23 subunit alpha) (IL-23-A) (Interleukin-23 subunit p19) (IL-23p19)
Gene: IL23A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.88 | 1.00 | 0.939 |
The method score is based on:
Property | Details |
---|---|
Experiments | 29997244, 11114383, 18708069, 18680750, 12023369 |
Identification Methods | affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, x-ray crystallography, anti bait coimmunoprecipitation, luminescence based mammalian interactome mapping |
Interaction Type | physical association, direct interaction, disulfide bond, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | IL12p40_C~IL23 |
Common GO terms | GO:0001916 - positive regulation of T cell mediated cytotoxicity GO:0002230 - positive regulation of defense response to virus by host GO:0002827 - positive regulation of T-helper 1 type immune response GO:0005125 - cytokine activity GO:0005576 - extracellular region and 28 others more... |
Homologous interactions | 2 |
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Last updated: 15 Jul 2024