HitPredict

Interactor 1: NOS2 (P29477)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC-NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2

Interactor 2: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11457725
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1144 Mm			1 192
+	Mm
		667792 NOS2_MOUSE (1-1144): 0: 1808: 100.00		RAC2_MOUSE (1-192): 6.16e-83: 245: 91.67
+	Hs
		718483 NOS2_HUMAN (1-1144): 0: 1775: 80.78		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		545231 NOS2_HUMAN (1-1144): 0: 1775: 80.78		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		560186 NCPR_HUMAN (496-1122): 0: 737: 29.06		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		545195 NCPR_HUMAN (496-1122): 0: 737: 29.06		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		560181 NCPR_HUMAN (496-1122): 0: 737: 29.06		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		560188 NCPR_HUMAN (496-1122): 0: 737: 29.06		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		560182 NCPR_HUMAN (496-1122): 0: 737: 29.06		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		560184 NCPR_HUMAN (496-1122): 0: 737: 29.06		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436146 NCPR_HUMAN (496-1122): 0: 737: 29.06		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45