HitPredict

Interactor 1: MCM5 (P29496)
Minichromosome maintenance protein 5 (EC 3.6.4.12) (Cell division control protein 46)
Gene: MCM5

Interactor 2: MCM6 (P53091)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (Minichromosome maintenance protein 6)
Gene: MCM6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.956

The method score is based on:

Property Details
Experiments 11805826, 25313033, 25172955, 19106085, 28191893, 37968396, 21179020, 16429126
Identification Methods tandem affinity purification, biochemical, affinity chromatography technology, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM6_C, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM6_C~MCM_lid, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 14 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 775
Sc

1 1017
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+ Mm
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+ Sp

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Last updated: 15 Jul 2024