Interactor 1: MCM5 (P29496)
Minichromosome maintenance protein 5 (EC 3.6.4.12) (Cell division control protein 46)
Gene: MCM5

Interactor 2: PSF1 (Q12488)
DNA replication complex GINS protein PSF1 (Partner of Sld five 1)
Gene: PSF1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 37968396, 25313033, 21362622, 21868389
Identification Methods affinity chromatography technology, biochemical, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~Sld5, MCM_N~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0006268 - DNA unwinding involved in DNA replication
GO:0031261 - DNA replication preinitiation complex
GO:0031298 - replication fork protection complex
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 775
Sc

1 208
+ Hs
+ Dm
+ Hs
+ Sc
+ Ce
+ Hs
+ Sc
+ Ce
+ Sc
+ Dm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024