HitPredict

Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: RL11 (P62913)
Large ribosomal subunit protein uL5 (60S ribosomal protein L11) (CLL-associated antigen KW-12)
Gene: RPL11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

The method score is based on:

Property	Details
Experiments	23169665, 15195100, 36880596
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006605 - protein targeting and 4 others more... GO:0031625 - ubiquitin protein ligase binding GO:0050821 - protein stabilization GO:1901798 - positive regulation of signal transduction by p53 class mediator GO:2000059 - negative regulation of ubiquitin-dependent protein catabolic process
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	882
Hs

1	178

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024