Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.764

The method score is based on:

Property Details
Experiments 25497731, 28851805, 11948183, 31879127, 34795231, 36880596, 19380586, 22875967, 9885291, 17344210, 19217413, 17081985, 21057547, 17036045
Identification Methods x-ray crystallography, fluorescent resonance energy transfer, two hybrid, pull down, proximity labelling technology, affinity chromatography technology, unspecified method, protein complementation assay, bioluminescence resonance energy transfer, isothermal titration calorimetry and 3 others

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Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0016605 - PML body
and 6 others

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Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 882
Hs

1 101
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Last updated: 15 Jul 2024