HitPredict

Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: MAP1S (Q66K74)
Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) (Variable charge Y chromosome 2-interacting protein 1) (VCY2-interacting protein 1) (VCY2IP-1) [Cleaved into: MAP1S heavy chain; MAP1S light chain]
Gene: MAP1S

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36880596
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol and 1 others more... GO:0006915 - apoptotic process
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 882 Hs			1 1059
+	Hs
		668511 PML_HUMAN (1-882): 0: 902: 100.00		MAP1B_HUMAN (313-1059): 3.25e-37: 155: 16.80
+	Hs
		668685 PML_HUMAN (1-882): 0: 902: 100.00		MDC1_HUMAN (299-855): 4.53e-11: 69.7: 10.52
+	Hs
		668617 PML_HUMAN (1-882): 0: 902: 100.00		IF4G1_HUMAN (484-981): 1.2e-09: 64.7: 12.94
+	Hs
		668591 PML_HUMAN (1-882): 0: 902: 100.00		MAP1A_HUMAN (293-985): 7.59e-09: 62.3: 10.80
+	Hs
		1029524 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		MAP1S_HUMAN (16-1059): 0: 627: 100.00
+	Hs
		1146249 TRI36_HUMAN (55-384): 5.81e-17: 87.9: 18.51		MAP1S_HUMAN (16-1059): 0: 627: 100.00
+	Hs
		807710 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		MAP1B_HUMAN (313-1059): 3.25e-37: 155: 16.80
+	Hs
		1295419 TRI33_HUMAN (56-558): 4.27e-74: 265: 15.56		CHAP1_HUMAN (506-939): 5.71e-14: 78.5: 15.46
+	Hs
		1057027 TRI33_HUMAN (56-558): 4.27e-74: 265: 15.56		MDC1_HUMAN (299-855): 4.53e-11: 69.7: 10.52
+	Hs
		980027 TRI33_HUMAN (56-558): 4.27e-74: 265: 15.56		IF4G1_HUMAN (484-981): 1.2e-09: 64.7: 12.94
+	Hs
		1029750 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		CHAP1_HUMAN (506-939): 5.71e-14: 78.5: 15.46
+	Hs
		1029427 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		MDC1_HUMAN (299-855): 4.53e-11: 69.7: 10.52
+	Hs
		257607 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		ANR17_HUMAN (472-998): 4.9e-09: 63.1: 12.17
+	Hs
		944675 TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97		MAP1A_HUMAN (293-985): 7.59e-09: 62.3: 10.80
+	Hs
		170402 TIF1A_HUMAN (27-546): 1.94e-62: 231: 16.49		SRCAP_HUMAN (430-954): 2.32e-10: 67.3: 12.64
+	Hs
		170182 TIF1A_HUMAN (27-546): 1.94e-62: 231: 16.49		ANR17_HUMAN (472-998): 4.9e-09: 63.1: 12.17
+	Hs
		944708 TRI36_HUMAN (55-384): 5.81e-17: 87.9: 18.51		MAP1A_HUMAN (293-985): 7.59e-09: 62.3: 10.80