HitPredict

Interactor 1: NEDD8 (P29595)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Interactor 2: RIGI (Q6Q899)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23553835
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CARD_2~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 81 Mm			1 926
+	Hs
		321867 UBB_HUMAN (1-76): 8.19e-32: 111: 57.90		RIGI_HUMAN (1-925): 0: 598: 77.08
+	Zm
		45293 B6SHW9_MAIZE (1-76): 8.54e-34: 114: 56.58		A0A1D6QLQ7_MAIZE (144-804): 1.69e-96: 334: 18.71
+	Hs
		133967 RS27A_HUMAN (1-77): 1.85e-38: 126: 57.14		DDX3X_HUMAN (381-767): 3.01e-34: 142: 12.93
+	Hs
		1079560 NEDD8_HUMAN (1-81): 1.15e-31: 107: 98.77		DDX17_HUMAN (459-831): 9.96e-40: 159: 14.39
+	Sc
		408309 RS31_YEAST (1-70): 1.26e-31: 109: 52.86		DRS1_YEAST (242-611): 1.38e-36: 150: 14.25
+	Hs
		571471 NEDD8_HUMAN (1-81): 1.15e-31: 107: 98.77		DDX5_HUMAN (511-792): 5.62e-37: 150: 17.24
+	Sc
		408277 RS31_YEAST (1-70): 1.26e-31: 109: 52.86		DBP2_YEAST (459-777): 7.58e-35: 142: 12.89
+	Hs
		134059 NEDD8_HUMAN (1-81): 1.15e-31: 107: 98.77		DDX3X_HUMAN (381-767): 3.01e-34: 142: 12.93
+	Sc
		408348 RS31_YEAST (1-70): 1.26e-31: 109: 52.86		DBP8_YEAST (607-808): 1.05e-13: 76.4: 23.42