HitPredict

Interactor 1: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Interactor 2: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005516 - calmodulin binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007417 - central nervous system development GO:0051015 - actin filament binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 332 Hs			1 2364
+	Hs
		211629 TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71		ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58
+	Hs
		993278 TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71		ACTN3_HUMAN (41-776): 4.93e-97: 338: 33.73
+	Hs
		521586 TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71		ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25
+	Hs
		297814 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		513830 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		DMD_HUMAN (234-2093): 2.37e-21: 105: 9.67
+	Hs
		670019 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		669919 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		164571 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10