HitPredict

Interactor 1: GNA11 (P29992)
Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha)
Gene: GNA11

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 359 Hs			1 196
+	Hs
		670452 GNA11_HUMAN (1-359): 1.18e-165: 468: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		670448 GNA11_HUMAN (1-359): 1.18e-165: 468: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		436171 GNA11_HUMAN (1-359): 1.18e-165: 468: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		391375 GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		670444 GNA11_HUMAN (1-359): 1.18e-165: 468: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		670445 GNA11_HUMAN (1-359): 1.18e-165: 468: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		391369 GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		391372 GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		391307 GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		436127 GNAI3_HUMAN (7-358): 1.15e-160: 455: 50.57		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		564422 GNA11_HUMAN (1-359): 1.18e-165: 468: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		925172 GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900360 GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915590 GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		436248 GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		926567 GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		892308 GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		893881 GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		436301 GNA13_HUMAN (8-358): 1.24e-143: 413: 45.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		564471 GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74