Interactor 1: GNA11 (P29992)
Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha)
Gene: GNA11
Interactor 2: PLCB1 (Q9NQ66)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-I) (PLC-I) (Phospholipase C-beta-1) (PLC-beta-1)
Gene: PLCB1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12193606 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EF-hand_like~G-alpha, G-alpha~PLC-beta_C |
| Common GO terms | GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0007207 - phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway GO:0007213 - G protein-coupled acetylcholine receptor signaling pathway GO:0032024 - positive regulation of insulin secretion and 3 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
