Interactor 1: ITPR1 (P29994)
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5-trisphosphate receptor) (IP-3-R) (Inositol 1,4,5-trisphosphate receptor type 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)
Gene: ITPR1

Interactor 2: ITPR1 (P29994)
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5-trisphosphate receptor) (IP-3-R) (Inositol 1,4,5-trisphosphate receptor type 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)
Gene: ITPR1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.715

The method score is based on:

Property Details
Experiments 21827954, 26458101
Identification Methods 3D electron microscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ins145_P3_rec~Ins145_P3_rec, Ins145_P3_rec~MIR, Ins145_P3_rec~RIH_assoc, Ins145_P3_rec~RYDR_ITPR, Ion_trans~Ion_trans, MIR~MIR, MIR~RYDR_ITPR, RYDR_ITPR~RYDR_ITPR
Common GO terms GO:0000902 - cell morphogenesis
GO:0001666 - response to hypoxia
GO:0005220 - inositol 1,4,5-trisphosphate-gated calcium channel activity
GO:0005509 - calcium ion binding
GO:0005635 - nuclear envelope
and 60 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2750
Rn

1 2750
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ Oc
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Oc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024