HitPredict

Interactor 1: AL4A1 (P30038)
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)
Gene: ALDH4A1

Interactor 2: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 563 Hs			1 425
+	Hs
		676656 AL1B1_HUMAN (35-556): 0: 605: 23.25		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		670537 AL4A1_HUMAN (1-563): 0: 594: 100.00		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		1110321 AL1L2_HUMAN (32-551): 2.3e-178: 529: 21.55		GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56
+	Ce
		105518 G5ECV9_CAEEL (67-551): 1.57e-180: 534: 22.56		LIN53_CAEEL (272-421): 6.33e-22: 99.1: 21.52
+	Sc
		765947 ALDH4_YEAST (49-550): 0: 530: 22.33		HAT2_YEAST (225-423): 7.28e-19: 89.6: 11.82
+	Ce
		954043 Q8IG19_CAEEL (119-556): 3.29e-172: 495: 23.24		LIN53_CAEEL (272-421): 6.33e-22: 99.1: 21.52
+	Ce
		103406 G4RZC3_CAEEL (141-563): 1.27e-171: 494: 60.61		LIN53_CAEEL (272-421): 6.33e-22: 99.1: 21.52
+	Sc
		765951 ALDH6_YEAST (38-550): 1.91e-171: 496: 23.75		HAT2_YEAST (225-423): 7.28e-19: 89.6: 11.82