HitPredict

Interactor 1: ERP29 (P30040)
Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31)
Gene: ERP29

Interactor 2: RON (Q04912)
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Gene: MST1R

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0009986 - cell surface GO:0043406 - positive regulation of MAP kinase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 261 Hs			1 1400
+	Hs
		671792 PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49		RON_HUMAN (19-1400): 0: 1277: 100.00
+	Hs
		531803 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		RON_HUMAN (19-1400): 0: 1277: 100.00
+	Hs
		441417 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		MET_HUMAN (1-1391): 0: 1065: 32.44
+	Hs
		531732 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		EPHB2_HUMAN (557-1369): 6.07e-165: 525: 17.12
+	Hs
		531731 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		EPHA8_HUMAN (568-1368): 1.37e-159: 509: 17.12
+	Hs
		423118 PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17		FGFR1_HUMAN (767-1397): 8.56e-114: 379: 22.74
+	Hs
		507820 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		FGFR1_HUMAN (767-1397): 8.56e-114: 379: 22.74
+	Hs
		670584 ERP29_HUMAN (1-261): 6.75e-81: 245: 100.00		UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47
+	Hs
		531813 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		MERTK_HUMAN (1037-1348): 1.21e-59: 225: 37.65
+	Hs
		531806 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		TYRO3_HUMAN (1062-1348): 1.01e-59: 224: 41.95
+	Hs
		531743 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		RYK_HUMAN (1050-1348): 3.57e-61: 223: 39.42
+	Hs
		671724 PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49		UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47
+	Hs
		423154 PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17		UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47
+	Hs
		531740 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47
+	Hs
		423108 PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		435520 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		411391 PDIA6_HUMAN (13-251): 1.66e-29: 116: 17.48		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73
+	Hs
		411271 PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73
+	Hs
		411285 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73
+	Hs
		671953 PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49		PLXA1_HUMAN (382-925): 4.04e-43: 174: 21.99