Interactor 1: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Interactor 2: PRDX2 (P32119)
Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2)
Gene: PRDX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 27173435
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 1-cysPrx_C~1-cysPrx_C, 1-cysPrx_C~AhpC-TSA, AhpC-TSA~AhpC-TSA
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006979 - response to oxidative stress
GO:0008379 - thioredoxin peroxidase activity
GO:0032496 - response to lipopolysaccharide
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 256
Hs

1 198
+ Hs
+ Hs
+ Bt
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Os
+ At
+ Sp

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Last updated: 15 Jul 2024