Interactor 1: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.685

The method score is based on:

Property Details
Experiments 31046837, unassigned1853, 21850687, 24459295
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid, anti bait coimmunoprecipitation, protein kinase assay
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 5 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 256
Hs

1 2527
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Last updated: 15 Jul 2024