HitPredict

Interactor 1: TEAD1 (P30051)
Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13)
Gene: TEAD1

Interactor 2: YAP1 (P46938)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.723

The method score is based on:

Property Details
Experiments 11358867, 36657504, 22308401, 25751140, 21376238, 24882516
Identification Methods pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003143 - embryonic heart tube morphogenesis
GO:0005634 - nucleus
GO:0005667 - transcription regulator complex
GO:0010468 - regulation of gene expression
and 11 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 426
Mm

1 488
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024