HitPredict

Interactor 1: PEBP1 (P30086)
Phosphatidylethanolamine-binding protein 1 (PEBP-1) (HCNPpp) (Neuropolypeptide h3) (Prostatic-binding protein) (Raf kinase inhibitor protein) (RKIP) [Cleaved into: Hippocampal cholinergic neurostimulating peptide (HCNP)]
Gene: PEBP1

Interactor 2: TIE2 (Q02763)
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)
Gene: TEK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 187 Hs			1 1124
+	Hs
		671710 PEBP1_HUMAN (1-187): 1.01e-94: 274: 100.00		EPHA6_HUMAN (518-1122): 5.91e-155: 490: 22.07
+	Hs
		665148 PEBP1_HUMAN (1-187): 1.01e-94: 274: 100.00		EPHA2_HUMAN (442-1123): 7.37e-153: 483: 22.10
+	Hs
		665442 PEBP1_HUMAN (1-187): 1.01e-94: 274: 100.00		EPHA8_HUMAN (519-1110): 2.23e-152: 483: 21.58
+	Hs
		445828 PEBP1_HUMAN (1-187): 1.01e-94: 274: 100.00		ROS1_HUMAN (448-1123): 1.09e-128: 437: 24.41
+	Hs
		671648 PEBP1_HUMAN (1-187): 1.01e-94: 274: 100.00		MERTK_HUMAN (350-632): 2.4e-17: 89.7: 16.89