HitPredict

Interactor 1: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Interactor 2: TEX14 (Q8IWB6)
Inactive serine/threonine-protein kinase TEX14 (Protein kinase-like protein SgK307) (Sugen kinase 307) (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein)
Gene: TEX14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 1497
+	Hs
		384339 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Hs
		671724 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		UFO_HUMAN (250-614): 5.9e-113: 381: 19.68
+	Hs
		384104 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Hs
		423154 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		UFO_HUMAN (250-614): 5.9e-113: 381: 19.68
+	Hs
		423180 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		BLK_HUMAN (44-525): 6.52e-118: 381: 15.22
+	Hs
		337993 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		EGFR_HUMAN (270-483): 6.22e-10: 66.2: 23.04
+	Hs
		337456 PDIA2_HUMAN (356-501): 1e-23: 106: 22.30		ABL1_HUMAN (110-974): 1.81e-129: 432: 15.23
+	Hs
		385136 DJC10_HUMAN (27-244): 3.4e-31: 129: 17.39		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Hs
		385355 TMX3_HUMAN (375-482): 4.46e-27: 115: 37.27		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Gg
		94496 PDIA3_CHICK (1-494): 2.85e-153: 448: 80.57		KSYK_CHICK (288-489): 1.04e-10: 68.2: 25.49
+	Hs
		385431 ERP44_HUMAN (368-496): 4.41e-25: 109: 21.64		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Hs
		384191 PDIA4_HUMAN (376-505): 1.13e-23: 106: 32.84		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Hs
		674477 DJC10_HUMAN (27-244): 3.4e-31: 129: 17.39		UFO_HUMAN (250-614): 5.9e-113: 381: 19.68
+	Hs
		846491 DJC10_HUMAN (27-244): 3.4e-31: 129: 17.39		BLK_HUMAN (44-525): 6.52e-118: 381: 15.22
+	Hs
		531740 PDIA4_HUMAN (376-505): 1.13e-23: 106: 32.84		UFO_HUMAN (250-614): 5.9e-113: 381: 19.68
+	Hs
		522950 PDIA2_HUMAN (356-501): 1e-23: 106: 22.30		SRC_HUMAN (109-527): 1.77e-109: 359: 16.96
+	Hs
		412164 PDIA2_HUMAN (356-501): 1e-23: 106: 22.30		FYN_HUMAN (222-527): 1.72e-108: 357: 20.07
+	Hs
		433975 ERP44_HUMAN (368-496): 4.41e-25: 109: 21.64		LYN_HUMAN (88-525): 5.71e-105: 346: 17.59
+	Hs
		337778 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		EGFR_HUMAN (270-483): 6.22e-10: 66.2: 23.04
+	Hs
		338668 DJC10_HUMAN (27-244): 3.4e-31: 129: 17.39		EGFR_HUMAN (270-483): 6.22e-10: 66.2: 23.04