HitPredict

Interactor 1: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Interactor 2: DJC16 (Q9Y2G8)
DnaJ homolog subfamily C member 16 (Endoplasmic reticulum DNA J domain-containing protein 8) (ER-resident protein ERdj8) (ERdj8)
Gene: DNAJC16

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin, Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 782
+	Hs
		423398 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DJC16_HUMAN (1-782): 0: 955: 100.00
+	Mm
		653446 PDIA3_MOUSE (1-505): 1.35e-160: 467: 93.07		ERP44_MOUSE (148-504): 5.73e-50: 182: 12.60
+	Hs
		671948 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DJB11_HUMAN (7-232): 6.1e-36: 141: 26.38
+	Hs
		636249 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DNJB1_HUMAN (26-135): 5.33e-36: 140: 36.04
+	Hs
		671939 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DJB12_HUMAN (28-160): 6.64e-35: 138: 32.33
+	Hs
		671947 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DNJB9_HUMAN (9-152): 2.73e-36: 138: 34.72
+	Hs
		671722 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		PDIA3_HUMAN (103-251): 1.3e-11: 70: 13.07
+	Hs
		671862 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DJC10_HUMAN (56-248): 2.28e-11: 69.6: 12.00
+	Dm
		870429 Q3YMU0_DROME (1-500): 1.45e-116: 354: 44.64		PDI_DROME (158-513): 9.32e-52: 190: 12.10
+	Hs
		531739 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		PDIA4_HUMAN (121-245): 6.82e-10: 64.6: 16.92
+	Hs
		423380 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DJB11_HUMAN (7-232): 6.1e-36: 141: 26.38
+	Hs
		423372 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DJB12_HUMAN (28-160): 6.64e-35: 138: 32.33
+	Hs
		423379 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DNJB9_HUMAN (9-152): 2.73e-36: 138: 34.72
+	Sc
		572732 PDI_YEAST (13-484): 8.93e-89: 283: 27.09		SCJ1_YEAST (28-333): 2.17e-47: 174: 18.44
+	Sc
		628935 EUG1_YEAST (2-505): 1.02e-79: 259: 25.05		SCJ1_YEAST (28-333): 2.17e-47: 174: 18.44
+	Hs
		423107 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		PDIA1_HUMAN (80-244): 3.2e-12: 71.9: 14.79
+	Hs
		423286 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DJC10_HUMAN (56-248): 2.28e-11: 69.6: 12.00
+	Hs
		423123 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		PDIA4_HUMAN (121-245): 6.82e-10: 64.6: 16.92
+	Ce
		1089129 PDI1_CAEEL (7-500): 6.81e-103: 318: 29.86		PDI2_CAEEL (127-243): 2.98e-10: 65.3: 15.83