HitPredict

Interactor 1: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28330616
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 247
+	Hs
		672007 2AAA_HUMAN (1-589): 2.84e-166: 487: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Mm
		926823 2AAA_MOUSE (1-589): 2.29e-166: 488: 99.83		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		268651 SF3B1_HUMAN (12-589): 2.5e-28: 122: 13.20		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		268647 SF3B1_HUMAN (12-589): 2.5e-28: 122: 13.20		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		909683 PP4R4_HUMAN (13-411): 1.42e-12: 72.9: 16.71		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		904718 PP4R4_HUMAN (13-411): 1.42e-12: 72.9: 16.71		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982145 PP4R4_HUMAN (13-411): 1.42e-12: 72.9: 16.71		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		268664 SF3B1_HUMAN (12-589): 2.5e-28: 122: 13.20		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		927364 GCN1_HUMAN (28-589): 5.37e-25: 112: 16.01		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647159 GCN1_HUMAN (28-589): 5.37e-25: 112: 16.01		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		927378 TNPO1_HUMAN (24-483): 2.91e-20: 97.2: 15.05		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		683448 PP4R4_HUMAN (13-411): 1.42e-12: 72.9: 16.71		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927171 PP4R4_HUMAN (13-411): 1.42e-12: 72.9: 16.71		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647004 PP4R4_HUMAN (13-411): 1.42e-12: 72.9: 16.71		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		684123 PP4R4_HUMAN (13-411): 1.42e-12: 72.9: 16.71		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16