HitPredict

Interactor 1: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Interactor 2: 2A5D (Q14738)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta)
Gene: PPP2R5D

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 26496610, 27173435, 23555304, 28330616, 32296183, 18782753, 33961781, 19156129, 23443559, 19293187, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, pull down, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains B56~HEAT_2
Common GO terms GO:0000159 - protein phosphatase type 2A complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0019888 - protein phosphatase regulator activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 589
Hs

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Last updated: 15 Jul 2024