Interactor 1: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.715

The method score is based on:

Property Details
Experiments 21983832
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT~Pkinase, HEAT_2~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0030425 - dendrite
GO:0035556 - intracellular signal transduction
and 4 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 589
Hs

1 2527
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024